By L. Heilmeyer, H. Begemann, Helmut Löffler, Johann Rastetter, Torsten Haferlach
This sixth version of the atlas has built-in the 2001 WHO class and made use of figures and outlines to record lately defined sorts of leukemia and lymphoma. The latter contain leukemias of dendritic cells, infrequent lymphomas and chronic polyclonal B lymphocytosis, which takes a different position within the classification.
The quantity covers all of the microscopic tools in hematology that shape the root of prognosis in addition to the result of smooth immunologic, cytogenetic and molecular-genetic research. detailed emphasis is put on the cytogenetic and molecular-genetic characterization of organic entities that would shape the foundation for cutting edge therapies.
Normal effects and pathological findings are in comparison, and a few of the findings made in the course of treatment are depicted. All in all of the Atlas of scientific Hematology represents an entire and worthwhile reference paintings which may be found in each hematologic and oncologic division in addition to in scientific laboratories for on-line diagnostics and medical research.
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Extra info for Atlas of Clinical Hematology
Some monocytes contain azurophilic granules much finer than those seen in lymphocytes. The nucleus is seldom round; usually it is deeply indented and lobulated (often bean-shaped). Its loose, delicate chromatin pattern is unique among the blood cells. Clumps of chromatin may be found scattered among larger, chromatin-poor areas. Nucleoli are rarely present. 55 4 · Individual Cells Fig. 13 a – d a b c d IV 56 Chapter IV · Blood and Bone Marrow Fig.
In absolute terms, mitoses are more frequent than in the myeloblasts (Fig. 7 d – h). 39 4 · Individual Cells Fig. 7 a – d a b c d IV 40 Chapter IV · Blood and Bone Marrow Fig. 7 e – h IV e f g h 41 4 · Individual Cells Neutrophilic Myelocytes, Metamyelocytes, Band and Segmented Forms, also Eosinophilic and Basophilic Granulocytes and Tissue Basophils (Fig. 8 a – h) The offspring of the promyelocytes are the myelocytes (Fig. 8 a – e). Generally these cells are somewhat smaller than their immediate precursors, with diameters ranging from 14 to 20 lm.
The reticulum cells described and counted in cytologic preparations from bone marrow, lymph nodes, and spleen form a heterogeneous group. A large portion belong to the macrophage system and are derived from blood monocytes. They also include segregated vascular and sinus endothelial cells in addition to dendritic cells belonging to the stroma. The reticulum cells of the bone marrow constitute the reticular or spongy tissue of the bone marrow in which the actual hematopoietic cells reside. Apparently they perform important tasks relating to nutrition and differentiation of the blood cell precursors.